CBB752/CPSC452/CPSC752/MBB452/MBB752/MCDB452/MCDB752

http://www.gersteinlab.org/courses/452/

Discussion sections

Jan

1/21/2009

(5 PM and 8 PM)

Bass 205

Section 1

T.F. Smith and M.S. Waterman. (1981) Identification of common molecular subsequences. Journal of Molecular Biology,147(1): 195-7. PMID: 7265238. Article

Myers G. (1999) A Fast Bit-Vector Algorithm for Approximate String Matching Based on Dynamic Programming. Journal of the ACM, 46, 395-415. Article

1/28/2009

(5 PM and 8 PM)

Bass 205

Section 2
Altschul SF, Gish W, Miller W, Myers EW, Lipman DJ. (1990) Basic local alignment search tool. Journal of Molecular Biology, 215(3):403-10. PMID: 2231712. Article
Garnier J, Gibrat JF, Robson B. (1996) GOR method for predicting protein secondary structure from amino acid sequence.Methods in Enzymology,266: 540-53. PMID: 8743705. Article
Feb

2/04/2009

(5 PM and 8 PM)

Bass 205

Section 3

Michael Levitt and Mark Gerstein. (1998) A unified statistical framework for sequence comparison and structure comparison. Proc. Nat. Sci.,95(11): 5913-20. PMID: 9600892. Article

Liisa Holm and Chris Sander. (1993) Protein Structure Comparison by Alignment of Distance Matrices. J. Mol. Biol., 233, 123-138. PMID: 8377180. Article

2/11/2009

(5 PM and 8 PM)

Bass 205

Section 4

ML Connolly. (1983) Solvent-accessible surfaces of proteins and nucleic acids. Science, 221(4612): 709-13. PMID: 6879170. Article

Martin Karplus and J. Andrew McCammon. (2002) Molecular dynamics simulations of biomolecules. Nature Structural Biology,9, 646-52. PMID: 12198485. Article

2/18/2009

No Meeting This Week

(To be held at later date)

Section 5

S Stephens, D LaVigna, M DiLascio, J Luciano. (2006) Aggregation of Bioinformatics Data Using Semantic Web Technology. Web Semantics: Science, Services and Agents on the World Wide Web, 4(3): 216-21. Article

X Zhu, M Gerstein, M Snyder. (2007) Getting connected: analysis and principles of biological networks. Genes and Development, 21, 1010-24. Article

2/25/2009

(5 PM and 8 PM)

Bass 205

Section 6

JC Venter, et al. (2004) Environmental genome shotgun sequencing of the Sargasso Sea. Science, 304(5667): 66-74. PMID: 15001713. Article

CR Woese, O Kandler, ML Wheelis. (1990) Towards a natural system of organisms: proposal for the domains Archaea, Bacteria, and Eucarya.Proc. Nat. Acad. Sci.,87(12): 4576-9. Article
Mar

3/04/2009

(5 PM and 8 PM)

Bass 205

Section 7

Tarca AL, Carey VJ, Chen XW, Romero R, Drăghici S. (2007) Machine learning and its applications to biology. PLoS Comput Biol.,26: e116. PMID: 17604446. Article

Kingsford C and Salzberg SL. (2008) What are decision trees? Nature Biotech,26, 1011-1013. Article

3/25/2009

Section 8

Alter O, Brown PO, Botstein D. (2000) Singular value decomposition for genome-wide expression data processing and modeling. Proc Nat Acad Sci USA,29:97(18), 10101-6. PMID: 10963673. Article

van 't Veer et al. (2002) Gene expression profiling predicts clinical outcome of breast cancer. Nature,415, 530-6. Article
April

4/01/2009

(6 PM and 8 PM)

Bass 205

Section 9

DeRisi JL, Iyer VR, and Brown PO. (1997) Exploring the Metabolic and Genetic Control of Gene Expression on a Genomic Scale. Science, 278(5338): 680-6. Article

Iyer VR, Horak CE, Scafe CS, Botstein D, Snyder M, and Brown PO. (2001) Genomic binding sites of the yeast cell-cycle transcription factors SBF and MBF. Nature,409, 533-8. Article

4/08/2009

(5 PM and 8 PM)

Bass 205

Section 10

Zhu H, et al. (2001) Global analysis of protein activities using proteome chips. Science, 293(5537): 2101-5.

PMID: 11474067. Article

Hughes TR, et al. (2000) Functional discovery via a compendium of expression profiles. Cell, 102(1): 109-26. Article

4/15/2009

(5 PM and 8 PM)

Bass 205

Section 11

Pop M, Phillippy A, Delcher AL, Salzberg SL. (2004) Comparative genome assembly. Brief Bioinform., 5(3): 237-48. PMID: 15383210. Article

Mardis ER. (2008) Next-generation DNA sequencing methods. Annu Rev Genomics Hum Genet., 9: 387-402. Article

Programming Assignments

Assignment 1: Due 02/05/2009 by 5 PM
Input File, Assignment

Assignment 2: Due 02/25/2009 by 5 PM
Training Set, Test Set, Assignment

Related pages

Outline of Topics