CBB752/CPSC452/CPSC752/MBB452/MBB752/MCDB452/MCDB752

http://www.gersteinlab.org/courses/452/

Discussion sections

Jan

21 (7:00-8:00pm, SHM C103) or

22 (5:00-6:00pm, BASS 405)

Section 1

Keelins, P.J. (2001) Parasites go the full monty. Nature, 414(6862), 450-3. PMID: 11719785
Germot A, Philippe H, Le Guyader H. Evidence for loss of mitochondria in Microsporidia from a mitochondrial-type HSP70 in Nosema locustae. Mol Biochem Parasitol, 87(2), 159-68. PMID: 9247927

28 (7:00-8:00pm, SHM C103) or

29 (5:00-6:00pm, BASS 405)

Section 2
 Doolittle W.F. (1999) Phylogenetic classification and the universal tree. Science, 284(5423), 2124-9. PMID: 10381871
Sali A. et al. (2003) From words to literature in structural proteomics. Nature, 422(6928), 216-25. PMID: 12634795
Feb

4 (7:00-8:00pm, SHM C103) or

5 (5:00-6:00pm, BASS 405)
Section 3
 DeRisi J.L., Iyer V.R. and Brown P.O. (1997) Exploring the metabolic and genetic control of gene expression on a genomic scale. Science, 278(5338), 680-6. PMID: 9381177
Golub T.R. et al. (1999) Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science, 286(5439), 531-7. PMID: 10521349

11 (7:00-8:00pm, SHM C103) or

12 (5:00-6:00pm, BASS 405)
Section 4
 Mello CC, Conte D Jr. Revealing the world of RNA interference. Nature, 431(7006), 338-42. PMID: 15372040
Hughes T.R. et al. (2000) Functional Discovery via a Compendium of Expression Profiles. Cell, 102(1), 109-26. PMID: 10929718

18 (7:00-8:00pm, SHM C103)

or 19 (5:00-6:00pm, BASS 405)
Section 5
Hohn MJ, Park HS, O'Donoghue P, Schnitzbauer M, Söll D. Emergence of the universal genetic code imprinted in an RNA record. PNAS, 103(48), 18095-100. PMID: 17110438
Raes J, Harrington ED, Singh AH, Bork P. Protein function space: viewing the limits or limited by our view? Current Opin Struct Biol, 17(3), 362-9. PMID: 17574832

25 (7:00-8:00pm, SHM C103) or

26 (5:00-6:00pm, BASS 405)

Section 6
Vetsigian K., Woese C. and Goldenfeld N. (2006) Collective evolution and the genetic code. PNAS, 103(28), 10696-701. PMID: 16818880
Mar
No section the week of Mar 3 due to the midterm.
  

24 (7:00-8:00pm, SHM C103) or

25 (5:00-6:00pm, BASS 405)

Section 7
 Luscombe N.M., Greenbaum D. and Gerstein M. (2001) What is bioinformatics? A proposed definition and overview of the field. Methods Inf Med., 40(4), 346-58. PMID: 11552348
Greenbaum D. et al. (2001) Interrelating different types of genomic data, from proteome to secretome: 'oming in on function. Genome Res., 11(9), 1463-8. PMID: 11544189
Apr

Mar 31 (7:00-8:00pm, SHM C103) or

Apr 1 (5:00-6:00pm, BASS 405)

Section 8
 Needleman S.B. and Wunsch C.D. (1970) A general method applicable to the search for similarities in the amino acid sequence of two proteins. J Mol Biol., 48(3), 443-53. PMID: 5420325
Eddy S.R. (1998) Profile hidden Markov models. Bioinformatics, 14(9), 755-63. PMID: 9918945

7 (7:00-8:00pm, SHM C103) or

8 (5:00-6:00pm, BASS 405)

Section 9
 Altschul S.F. et al. (1997) Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res., 25(17), 3389-402. PMID: 9254694
Altschul S.F. et al. (1994) Issues in searching molecular sequence databases. Nat Genet., 6(2), 119-29. PMID: 8162065

14 (7:00-8:00pm, SHM C103) or

15 (5:00-6:00pm, BASS 405)

Section 10
 Garnier J., Gibrat J.F. and Robson B. (1996) GOR method for predicting protein secondary structure from amino acid sequence. Methods Enzymol., 266, 540-53. PMID: 8743705 ScienceDirect link
Roberts L. (2001) Controversial From the Start. Science, 291, 1182-8. link

21 (7:00-8:00pm, SHM C103) or

22(5:00-6:00pm, BASS 405)

Section 11
Ginalski K, et al. (2005) Practical lessons from protein structure prediction. Nucleic Acids Res., 33(6), 1874-91. PMID: 15805122
 

Related pages

Outline of Topics