Predicting Essential Genes in Fungal Genomes
By Michael Seringhaus†, Alberto Paccanaro†, Anthony Borneman, Michael Snyder and Mark Gerstein*

* To whom correspondence should be addressed: mark.gerstein@yale.edu
† These authors contributed equally to this work.


Supplementary Data Website "PredESS"
Main URL: http://www.gersteinlab.org/proj/predess/
Gerstein Group Homepage: http://www.gersteinlab.org/

Contents of this Website:

  1. Supplementary Figures
  2. Training the Machine Learning Classifier (S.cerevisiae)
  3. Predicting Essential Genes (S.mikatae)
  4. Supplementary Prediction Sets (S.pombe, S.bayanus)
  5. Control: Randomization of 'ESSENTIAL' Label

 

1. Supplementary Figures


 

2. Training the Machine Learning Classifier (S.cerevisiae)

S.cerevisiae


 

3. Predicting Essential Genes (S.mikatae)

S.mikatae


4. Supplementary Prediction Sets (S.pombe, S.bayanus)

S.pombe

S.bayanus


5. Control: Randomization of 'ESSENTIAL' Label

As a control experiment, the 'essential' label was randomized among S.cerevisiae genes and our classifier was re-trained on this mock 'RANDOM-ESS' data.

This classifier was then applied to S.mikatae to predict 'essential' genes. These results are here:


This Website © 2006 Gerstein Lab. HTML by Michael Seringhaus.