Mark Gerstein is the Albert L Williams professor of Biomedical Informatics at Yale University. He is co-director the Yale Computational Biology and Bioinformatics Program, and has appointments in the Department of Molecular Biophysics and Biochemistry and the Department of Computer Science. He received his AB in physics summa cum laude from Harvard College in 1989 and his PhD in chemistry from Cambridge in 1993. He did post-doctoral work at Stanford and took up his post at Yale in early 1997. Since then he has received a number of young investigator awards (e.g. from the Navy and the Keck foundation) and has published appreciably in scientific journals. He has >250 publications in total, with a number of them in prominent journals, such as Science, Nature, and Scientific American. (His current publication list is at http://papers.gersteinlab.org .) His research is focused on bioinformatics, and he is particularly interested in large-scale integrative surveys, biological database design, macromolecular geometry, molecular simulation, human genome annotation, gene expression analysis, and data mining.